Pharmacokinetics of enflicoxib in dogs: Effects of prandial state and repeated administration

The pharmacokinetics of enflicoxib were evaluated in both a bioavailability study and a multi‐dose safety study in Beagle dogs. When administered at 8 mg/kg, the oral bioavailability (F) of enflicoxib was 44.1% in fasted dogs, but F increased to 63.4% under post prandial conditions. Enflicoxib is ra...

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Detalles Bibliográficos
Autores principales: Homedes, Josep, Salichs, Marta, Solà, Josep, Menargues, Angel, Cendrós, Josep‐Maria, Encina, Gregorio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9291756/
https://www.ncbi.nlm.nih.gov/pubmed/34160092
http://dx.doi.org/10.1111/jvp.12995

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9291756/
https://www.ncbi.nlm.nih.gov/pubmed/34160092
http://dx.doi.org/10.1111/jvp.12995

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