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Phenylbutyrate, a branched‐chain amino acid keto dehydrogenase activator, promotes branched‐chain amino acid metabolism and induces muscle catabolism in C2C12 cells
NEW FINDINGS: What is the central question of this study? The compound sodium phenylbutyrate (PB) has been shown to promote branched‐chain amino acid (BCAA) catabolism, and as such has been proposed as a treatment for disorders with enhanced BCAA levels: does PB induce muscle protein catabolism by f...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9291829/ https://www.ncbi.nlm.nih.gov/pubmed/33369803 http://dx.doi.org/10.1113/EP089223 |