Phenylbutyrate, a branched‐chain amino acid keto dehydrogenase activator, promotes branched‐chain amino acid metabolism and induces muscle catabolism in C2C12 cells

NEW FINDINGS: What is the central question of this study? The compound sodium phenylbutyrate (PB) has been shown to promote branched‐chain amino acid (BCAA) catabolism, and as such has been proposed as a treatment for disorders with enhanced BCAA levels: does PB induce muscle protein catabolism by f...

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Detalles Bibliográficos
Autores principales: Crossland, Hannah, Smith, Kenneth, Idris, Iskandar, Phillips, Bethan E., Atherton, Philip J, Wilkinson, Daniel J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9291829/
https://www.ncbi.nlm.nih.gov/pubmed/33369803
http://dx.doi.org/10.1113/EP089223

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