Ethanol‐induced formation of colorectal tumours and precursors in a mouse model of Lynch syndrome

Lynch syndrome (LS) confers inherited cancer predisposition due to germline mutations in a DNA mismatch repair (MMR) gene, e.g. MSH2. MMR is a repair pathway for removal of base mismatches and insertion/deletion loops caused by endogenous and exogenous factors. Loss of MMR through somatic alteration...

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Detalles Bibliográficos
Autores principales: Cerretelli, Guia, Zhou, Ying, Müller, Mike F, Adams, David J, Arends, Mark J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2021
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9291843/
https://www.ncbi.nlm.nih.gov/pubmed/34543445
http://dx.doi.org/10.1002/path.5796

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9291843/
https://www.ncbi.nlm.nih.gov/pubmed/34543445
http://dx.doi.org/10.1002/path.5796

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