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Ethanol‐induced formation of colorectal tumours and precursors in a mouse model of Lynch syndrome
Lynch syndrome (LS) confers inherited cancer predisposition due to germline mutations in a DNA mismatch repair (MMR) gene, e.g. MSH2. MMR is a repair pathway for removal of base mismatches and insertion/deletion loops caused by endogenous and exogenous factors. Loss of MMR through somatic alteration...
Autores principales: | Cerretelli, Guia, Zhou, Ying, Müller, Mike F, Adams, David J, Arends, Mark J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9291843/ https://www.ncbi.nlm.nih.gov/pubmed/34543445 http://dx.doi.org/10.1002/path.5796 |
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