Structural determinants of TRPV4 inhibition and identification of new antagonists with antiviral activity

BACKGROUND AND PURPOSE: The transient receptor potential vanilloid 4 (TRPV4) cation channel participates in multiple physiological processes and is also at the core of different diseases, making this channel an interesting pharmacological target with therapeutic potential. However, little is known a...

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Detalles Bibliográficos
Autores principales: Doñate‐Macian, Pablo, Duarte, Yorley, Rubio‐Moscardo, Fanny, Pérez‐Vilaró, Gemma, Canan, Jonathan, Díez, Juana, González‐Nilo, Fernando, Valverde, Miguel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9291951/
https://www.ncbi.nlm.nih.gov/pubmed/32959389
http://dx.doi.org/10.1111/bph.15267

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9291951/
https://www.ncbi.nlm.nih.gov/pubmed/32959389
http://dx.doi.org/10.1111/bph.15267

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