In vivo Treg expansion under costimulation blockade targets early rejection and improves long‐term outcome

CTLA4Ig has been shown to improve kidney allograft function, but an increased frequency of early rejection episodes poses a major obstacle for more widespread clinical use. The deleterious effect of CTLA4Ig on Treg numbers provides a possible explanation for graft injury. Therefore, we aimed at impr...

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Detalles Bibliográficos
Autores principales: Schwarz, Christoph, Mahr, Benedikt, Muckenhuber, Moritz, Weijler, Anna Marianne, Unger, Lukas Walter, Pilat, Nina, Latus, Michaela, Regele, Heinz, Wekerle, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Brief Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9292010/
https://www.ncbi.nlm.nih.gov/pubmed/34152692
http://dx.doi.org/10.1111/ajt.16724

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9292010/
https://www.ncbi.nlm.nih.gov/pubmed/34152692
http://dx.doi.org/10.1111/ajt.16724

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