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The antigen‐binding moiety in the driver's seat of CARs

Immuno‐oncology has been at the forefront of cancer treatment in recent decades. In particular immune checkpoint and chimeric antigen receptor (CAR)‐T cell therapy have achieved spectacular results. Over the years, CAR‐T cell development has followed a steady evolutionary path, focusing on increasin...

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Detalles Bibliográficos
Autores principales: Hanssens, Heleen, Meeus, Fien, De Veirman, Kim, Breckpot, Karine, Devoogdt, Nick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9292017/
https://www.ncbi.nlm.nih.gov/pubmed/34028069
http://dx.doi.org/10.1002/med.21818