Cargando…
Deriving time-concordant event cascades from gene expression data: A case study for Drug-Induced Liver Injury (DILI)
Adverse event pathogenesis is often a complex process which compromises multiple events ranging from the molecular to the phenotypic level. In toxicology, Adverse Outcome Pathways (AOPs) aim to formalize this as temporal sequences of events, in which event relationships should be supported by causal...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2022
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9292124/ https://www.ncbi.nlm.nih.gov/pubmed/35687583 http://dx.doi.org/10.1371/journal.pcbi.1010148 |