Clinical evaluation of the potential drug–drug interactions of savolitinib: Interaction with rifampicin, itraconazole, famotidine or midazolam

AIMS: We investigated savolitinib pharmacokinetics (PK) when administered alone or in combination with rifampicin, itraconazole or famotidine, and investigated midazolam PK when administered with or without savolitinib in healthy males. METHODS: Savolitinib PK was evaluated before/after: rifampicin...

Descripción completa

Detalles Bibliográficos
Autores principales: Ren, Song, Vishwanathan, Karthick, Cantarini, Mireille, Frewer, Paul, Hara, Indira, Scarfe, Graeme, Burke, Wendy, Schalkwijk, Stein, Li, Yan, Han, David, Goldwater, Ronald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9292161/
https://www.ncbi.nlm.nih.gov/pubmed/34322894
http://dx.doi.org/10.1111/bcp.14994

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9292161/
https://www.ncbi.nlm.nih.gov/pubmed/34322894
http://dx.doi.org/10.1111/bcp.14994

Ejemplares similares