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Population pharmacokinetics of roxadustat in Japanese dialysis‐dependent chronic kidney disease patients with anaemia

AIMS: Our objective was to develop a population pharmacokinetic (PK) model to describe roxadustat plasma concentrations in Japanese dialysis‐dependent chronic kidney disease (DD‐CKD) patients with renal anaemia and to identify the covariate factors that affect exposure of roxadustat. METHODS: In tot...

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Detalles Bibliográficos
Autores principales: Takada, Akitsugu, Shibata, Tomohisa, Shiga, Takanori, Groenendaal‐van de Meent, Dorien, Komatsu, Kanji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9292185/
https://www.ncbi.nlm.nih.gov/pubmed/34350625
http://dx.doi.org/10.1111/bcp.15023