Comparative genomic analysis of human GLI2 locus using slowly evolving fish revealed the ancestral gnathostome set of early developmental enhancers

BACKGROUND: The zinc finger‐containing transcription factor Gli2, is a key mediator of Hedgehog (Hh) signaling and participates in embryonic patterning of various organs including the central nervous system (CNS) and limbs. Abnormal expression of Gli2 can impede the transcription of Hh target genes...

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Detalles Bibliográficos
Autores principales: Ali, Shahid, Arif, Irum, Iqbal, Ayesha, Hussain, Irfan, Abrar, Muhammad, Khan, Muhammad Ramzan, Shubin, Neil, Abbasi, Amir Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9292287/
https://www.ncbi.nlm.nih.gov/pubmed/33381902
http://dx.doi.org/10.1002/dvdy.291

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9292287/
https://www.ncbi.nlm.nih.gov/pubmed/33381902
http://dx.doi.org/10.1002/dvdy.291

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