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Comparative genomic analysis of human GLI2 locus using slowly evolving fish revealed the ancestral gnathostome set of early developmental enhancers
BACKGROUND: The zinc finger‐containing transcription factor Gli2, is a key mediator of Hedgehog (Hh) signaling and participates in embryonic patterning of various organs including the central nervous system (CNS) and limbs. Abnormal expression of Gli2 can impede the transcription of Hh target genes...
Autores principales: | Ali, Shahid, Arif, Irum, Iqbal, Ayesha, Hussain, Irfan, Abrar, Muhammad, Khan, Muhammad Ramzan, Shubin, Neil, Abbasi, Amir Ali |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9292287/ https://www.ncbi.nlm.nih.gov/pubmed/33381902 http://dx.doi.org/10.1002/dvdy.291 |
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