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PERSEPT 3: A phase 3 clinical trial to evaluate the haemostatic efficacy of eptacog beta (recombinant human FVIIa) in perioperative care in subjects with haemophilia A or B with inhibitors

INTRODUCTION: Surgical procedures in persons with haemophilia A or B with inhibitors (PwHABI) require the use of bypassing agents (BPA) and carry a high risk of complications. Historically, only two BPAs have been available; these are reported to have variable responses. AIM: To prospectively evalua...

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Detalles Bibliográficos
Autores principales: Escobar, Miguel, Luck, James, Averianov, Yevhenii, Ducore, Jonathan, Fernández, Maria Fernanda López, Giermasz, Adam, Hart, Daniel P., Journeycake, Janna, Kessler, Craig, Leissinger, Cindy, Mahlangu, Johnny, Martinez, Laura Villarreal, Miesbach, Wolfgang, Mitha, Ismail Haroon, Quon, Doris, Reding, Mark T., Schved, Jean‐François, Stasyshyn, Oleksandra, Vilchevska, Kateryna V., Wang, Michael, Windyga, Jerzy, Alexander, W. Allan, Al‐Sabbagh, Ahmad, Bonzo, Daniel, Mitchell, Ian S., Wilkinson, Thomas A., Hermans, Cédric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9292306/
https://www.ncbi.nlm.nih.gov/pubmed/34614267
http://dx.doi.org/10.1111/hae.14418