Population Pharmacokinetic Model Development and Simulation for Recombinant Erwinia Asparaginase Produced in Pseudomonas fluorescens (JZP‐458)

JZP‐458 is a recombinant Erwinia asparaginase produced using a novel Pseudomonas fluorescens expression platform that yields an enzyme expected to lack immunologic cross‐reactivity to Escherichia coli–derived asparaginases. It is being developed as part of a multiagent chemotherapeutic regimen to tr...

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Detalles Bibliográficos
Autores principales: Lin, Tong, Dumas, Todd, Kaullen, Josh, Berry, N. Seth, Choi, Mi Rim, Zomorodi, Katie, Silverman, Jeffrey A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9292349/
https://www.ncbi.nlm.nih.gov/pubmed/34310867
http://dx.doi.org/10.1002/cpdd.1002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9292349/
https://www.ncbi.nlm.nih.gov/pubmed/34310867
http://dx.doi.org/10.1002/cpdd.1002

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