Overexpression of PD‐L1 in gingival basal keratinocytes reduces periodontal inflammation in a ligature‐induced periodontitis model

BACKGROUND: The immune checkpoint programmed cell death 1 (PD‐1): PD‐1 ligand 1 (PD‐L1) pathway plays a crucial role in maintaining immune tolerance and preventing tissue damages by excessive immune responses. PD‐L1 is physiologically expressed and upregulated in keratinocytes (KCs) in the oral cavi...

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Detalles Bibliográficos
Autores principales: Wongtim, Keeratika, Ikeda, Eri, Ohno, Tatsukuni, Nagai, Shigenori, Okuhara, Shigeru, Kure, Keitetsu, Azuma, Miyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Translational Periodontology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9292381/
https://www.ncbi.nlm.nih.gov/pubmed/34021604
http://dx.doi.org/10.1002/JPER.21-0017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9292381/
https://www.ncbi.nlm.nih.gov/pubmed/34021604
http://dx.doi.org/10.1002/JPER.21-0017

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