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Demethoxycurcumin induces apoptosis in HER2 overexpressing bladder cancer cells through degradation of HER2 and inhibiting the PI3K/Akt pathway

Bladder cancer is the most common malignancy of the urinary tract and arising from the epithelial lining of the urinary bladder. Resistance to cytotoxic therapies is associated with overexpression of oncogenic proteins; including HER2, and Akt in chemotherapy resistance of bladder cancer. Various st...

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Detalles Bibliográficos
Autores principales: Kao, Chien‐Chang, Cheng, Yi‐Ching, Yang, Ming‐Hsin, Cha, Tai‐Lung, Sun, Guang‐Huan, Ho, Chi‐Tang, Lin, Ying‐Chao, Wang, Hao‐Kuang, Wu, Sheng‐Tang, Way, Tzong‐Der
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9292507/
https://www.ncbi.nlm.nih.gov/pubmed/34291863
http://dx.doi.org/10.1002/tox.23332