Mimicking human riboflavin responsive neuromuscular disorders by silencing flad‐1 gene in C. elegans : Alteration of vitamin transport and cholinergic transmission

Riboflavin (Rf), or vitamin B2, is the precursor of FMN and FAD, redox cofactors of several dehydrogenases involved in energy metabolism, redox balance and other cell regulatory processes. FAD synthase, coded by FLAD1 gene in humans, is the last enzyme in the pathway converting Rf into FAD. Mutation...

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Detalles Bibliográficos
Autores principales: Leone, Piero, Tolomeo, Maria, Piancone, Elisabetta, Puzzovio, Pier Giorgio, De Giorgi, Carla, Indiveri, Cesare, Di Schiavi, Elia, Barile, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2021
Materias:
Cofactor Assembly and INSERTION_1: Flavins
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9292511/
https://www.ncbi.nlm.nih.gov/pubmed/34558787
http://dx.doi.org/10.1002/iub.2553

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9292511/
https://www.ncbi.nlm.nih.gov/pubmed/34558787
http://dx.doi.org/10.1002/iub.2553

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