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Direct Conversion of Hydrazones to Amines using Transaminases

Transaminase enzymes (TAms) have been widely used for the amination of aldehydes and ketones, often resulting in optically pure products. In this work, transaminases were directly reacted with hydrazones in a novel approach to form amine products. Several substrates were investigated, including thos...

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Detalles Bibliográficos
Autores principales: Carter, Eve M., Subrizi, Fabiana, Ward, John M., Sheppard, Tom D., Hailes, Helen C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9292518/
https://www.ncbi.nlm.nih.gov/pubmed/35874927
http://dx.doi.org/10.1002/cctc.202101008