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Tryptophan‐derived serotonin‐kynurenine balance in immune activation and intestinal inflammation

Endogenous tryptophan metabolism pathways lead to the production of serotonin (5‐hydroxytryptamine; 5‐HT), kynurenine, and several downstream metabolites which are involved in a multitude of immunological functions in both health and disease states. Ingested tryptophan is largely shunted to the kynu...

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Detalles Bibliográficos
Autores principales: Haq, Sabah, Grondin, Jensine A., Khan, Waliul I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9292703/
https://www.ncbi.nlm.nih.gov/pubmed/34473368
http://dx.doi.org/10.1096/fj.202100702R