Cripto favors chondrocyte hypertrophy via TGF‐β SMAD1/5 signaling during development of osteoarthritis

Chondrocytes in mice developing osteoarthritis (OA) exhibit an aberrant response to the secreted cytokine transforming growth factor (TGF)‐β, consisting in a potentiation of intracellular signaling downstream of the transmembrane type I receptor kinase activin receptor‐like kinase (ALK)1 against can...

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Detalles Bibliográficos
Autores principales: Garcia de Vinuesa, Amaya, Sanchez‐Duffhues, Gonzalo, Blaney‐Davidson, Esmeralda, van Caam, Arjan, Lodder, Kirsten, Ramos, Yolande, Kloppenburg, Margreet, Meulenbelt, Ingrid, van der Kraan, Peter, Goumans, Marie‐José, ten Dijke, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2021
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9292799/
https://www.ncbi.nlm.nih.gov/pubmed/34357595
http://dx.doi.org/10.1002/path.5774

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9292799/
https://www.ncbi.nlm.nih.gov/pubmed/34357595
http://dx.doi.org/10.1002/path.5774

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