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Reduced brain volume and white matter alterations in Shank3‐deficient rats

Mutations and deletions in the SHANK3 gene cause the major neurodevelopmental features of Phelan–McDermid syndrome (PMS), which is characterized by intellectual disability, autism spectrum disorder, and sensory hyporeactivity. SHANK3 encodes a key structural component of excitatory synapses importan...

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Detalles Bibliográficos
Autores principales: Golden, Carla E. M., Wang, Victoria X., Harony‐Nicolas, Hala, Hof, Patrick R., Buxbaum, Joseph D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9292834/
https://www.ncbi.nlm.nih.gov/pubmed/34313403
http://dx.doi.org/10.1002/aur.2568