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The broad pathogenetic role of TCF7L2 in human diseases beyond type 2 diabetes

The TCF7L2 protein is a key transcriptional effector of the Wnt/β‐catenin signaling pathway, regulating gene expression. It was initially identified in cancer research and embryologic developmental studies. Later, the TCF7L2 gene was linked to type 2 diabetes (T2D), implicating TCF7L2 and Wnt‐signal...

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Detalles Bibliográficos
Autores principales: del Bosque‐Plata, Laura, Hernández‐Cortés, Eduardo Pavel, Gragnoli, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9292842/
https://www.ncbi.nlm.nih.gov/pubmed/34612510
http://dx.doi.org/10.1002/jcp.30581