A mutation in desmin makes skeletal muscle less vulnerable to acute muscle damage after eccentric loading in rats

Desminopathy is the most common intermediate filament disease in humans. The most frequent mutation causing desminopathy in patients is a R350P DES missense mutation. We have developed a rat model with an analogous mutation in R349P Des. To investigate the role of R349P Des in mechanical loading, we...

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Detalles Bibliográficos
Autores principales: Langer, Henning T., Mossakowski, Agata A., Avey, Alec M., Wohlgemuth, Ross P., Smith, Lucas R., Zbinden‐Foncea, Herman, Baar, Keith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9292853/
https://www.ncbi.nlm.nih.gov/pubmed/34411340
http://dx.doi.org/10.1096/fj.202100711RR

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9292853/
https://www.ncbi.nlm.nih.gov/pubmed/34411340
http://dx.doi.org/10.1096/fj.202100711RR

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