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Pharmacokinetics, Safety, and Tolerability of Single‐ and Multiple‐Dose Once‐Daily Baricitinib in Healthy Chinese Subjects: A Randomized Placebo‐Controlled Study

The objective of this phase 1 study was to evaluate the pharmacokinetics, safety, and tolerability of baricitinib after single and multiple doses in healthy Chinese adults. Eligible subjects received a once‐daily dose of baricitinib 2, 4, or 10 mg or placebo on day 1 (single dose) and days 4 through...

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Detalles Bibliográficos
Autores principales: Zhao, Xia, Sheng, Xiao Yan, Payne, Christopher D., Zhang, Xin, Wang, Feng, Cui, Yi Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9292889/
https://www.ncbi.nlm.nih.gov/pubmed/32945153
http://dx.doi.org/10.1002/cpdd.868