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Updated results of the placebo‐controlled, phase III JAKARTA trial of fedratinib in patients with intermediate‐2 or high‐risk myelofibrosis

Fedratinib, an oral Janus kinase‐2 (JAK2) inhibitor, reduces splenomegaly and improves symptom burden in patients with myelofibrosis. Regulatory approval of fedratinib 400‐mg daily was based on results of an updated analysis of the pivotal phase III, placebo‐controlled JAKARTA trial in patients with...

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Detalles Bibliográficos
Autores principales: Pardanani, Animesh, Tefferi, Ayalew, Masszi, Tamás, Mishchenko, Elena, Drummond, Mark, Jourdan, Eric, Vannucchi, Alessandro, Jurgutis, Mindaugas, Ribrag, Vincent, Rambaldi, Alessandro, Koh, Liang Piu, Rose, Shelonitda, Zhang, Jun, Harrison, Claire
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9292894/
https://www.ncbi.nlm.nih.gov/pubmed/34331348
http://dx.doi.org/10.1111/bjh.17727