Chemoenzymatic Oxosulfonylation‐Bioreduction Sequence for the Stereoselective Synthesis of β‐Hydroxy Sulfones

A series of optically active β‐hydroxy sulfones has been obtained through an oxosulfonylation‐stereoselective reduction sequence in aqueous medium. Firstly, β‐keto sulfones were synthesized from arylacetylenes and sodium sulfinates to subsequently develop the carbonyl reduction in a highly selective...

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Detalles Bibliográficos
Autores principales: López‐Agudo, Marina, Ríos‐Lombardía, Nicolás, González‐Sabín, Javier, Lavandera, Iván, Gotor‐Fernández, Vicente
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9292901/
https://www.ncbi.nlm.nih.gov/pubmed/34409744
http://dx.doi.org/10.1002/cssc.202101313

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9292901/
https://www.ncbi.nlm.nih.gov/pubmed/34409744
http://dx.doi.org/10.1002/cssc.202101313

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