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A high-throughput yeast display approach to profile pathogen proteomes for MHC-II binding

T cells play a critical role in the adaptive immune response, recognizing peptide antigens presented on the cell surface by major histocompatibility complex (MHC) proteins. While assessing peptides for MHC binding is an important component of probing these interactions, traditional assays for testin...

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Detalles Bibliográficos
Autores principales: Huisman, Brooke D, Dai, Zheng, Gifford, David K, Birnbaum, Michael E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9292997/
https://www.ncbi.nlm.nih.gov/pubmed/35781135
http://dx.doi.org/10.7554/eLife.78589