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Additive and Emergent Catalytic Properties of Dimeric Unnatural Amino Acid Derivatives: Aldol and Conjugate Additions

Different densely substituted L‐ and D‐proline esters were prepared by asymmetric (3+2) cycloaddition reactions catalyzed by conveniently selected EhuPhos chiral ligands. The γ‐nitro‐2‐alkoxycarbonyl pyrrolidines thus obtained in either their endo or exo forms were functionalized and coupled to yiel...

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Detalles Bibliográficos
Autores principales: de Gracia Retamosa, María, Ruiz‐Olalla, Andrea, Agirre, Maddalen, de Cózar, Abel, Bello, Tamara, Cossío, Fernando P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9293019/
https://www.ncbi.nlm.nih.gov/pubmed/34453455
http://dx.doi.org/10.1002/chem.202102394