How Divalent Cations Interact with the Internal Channel Site of Guanine Quadruplexes

The formation of guanine quadruplexes (GQ) in DNA is crucial in telomere homeostasis and regulation of gene expression. Pollution metals can interfere with these DNA superstructures upon coordination. In this work, we study the affinity of the internal GQ channel site towards alkaline earth metal (M...

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Detalles Bibliográficos
Autores principales: Zaccaria, Francesco, van der Lubbe, Stephanie C. C., Nieuwland, Celine, Hamlin, Trevor A., Fonseca Guerra, Célia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9293024/
https://www.ncbi.nlm.nih.gov/pubmed/34435425
http://dx.doi.org/10.1002/cphc.202100529

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9293024/
https://www.ncbi.nlm.nih.gov/pubmed/34435425
http://dx.doi.org/10.1002/cphc.202100529

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