The molecular mechanism of RIG‐I activation and signaling

RIG‐I is our first line of defense against RNA viruses, serving as a pattern recognition receptor that identifies molecular features common among dsRNA and ssRNA viral pathogens. RIG‐I is maintained in an inactive conformation as it samples the cellular space for pathogenic RNAs. Upon encounter with...

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Detalles Bibliográficos
Autores principales: Thoresen, Daniel, Wang, Wenshuai, Galls, Drew, Guo, Rong, Xu, Ling, Pyle, Anna Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Invited Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9293153/
https://www.ncbi.nlm.nih.gov/pubmed/34514601
http://dx.doi.org/10.1111/imr.13022

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9293153/
https://www.ncbi.nlm.nih.gov/pubmed/34514601
http://dx.doi.org/10.1111/imr.13022

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