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TET‐Like Oxidation in 5‐Methylcytosine and Derivatives: A Computational and Experimental Study

The epigenetic marker 5‐methylcytosine (5mC) is an important factor in DNA modification and epigenetics. It can be modified through a three‐step oxidation performed by ten‐eleven‐translocation (TET) enzymes and we have previously reported that the iron(IV)‐oxo complex [Fe(O)(Py(5)Me(2)H)](2+) (1) ca...

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Detalles Bibliográficos
Autores principales: Jonasson, Niko S. W., Janßen, Rachel, Menke, Annika, Zott, Fabian L., Zipse, Hendrik, Daumann, Lena J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9293240/
https://www.ncbi.nlm.nih.gov/pubmed/34498783
http://dx.doi.org/10.1002/cbic.202100420