Cargando…

Localization of Na(+) channel clusters in narrowed perinexi of gap junctions enhances cardiac impulse transmission via ephaptic coupling: a model study

ABSTRACT: It has been proposed that when gap junctional coupling is reduced in cardiac tissue, action potential propagation can be supported via ephaptic coupling, a mechanism mediated by negative electric potentials occurring in narrow intercellular clefts of intercalated discs (IDs). Recent studie...

Descripción completa

Detalles Bibliográficos
Autores principales: Ivanovic, Ena, Kucera, Jan P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9293295/
https://www.ncbi.nlm.nih.gov/pubmed/34533834
http://dx.doi.org/10.1113/JP282105