Modeling‐Assisted Design of Thermostable Benzaldehyde Lyases from Rhodococcus erythropolis for Continuous Production of α‐Hydroxy Ketones

Enantiopure α‐hydroxy ketones are important building blocks of active pharmaceutical ingredients (APIs), which can be produced by thiamine‐diphosphate‐dependent lyases, such as benzaldehyde lyase. Here we report the discovery of a novel thermostable benzaldehyde lyase from Rhodococcus erythropolis R...

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Detalles Bibliográficos
Autores principales: Peng, Martin, Siebert, Dominik L., Engqvist, Martin K. M., Niemeyer, Christof M., Rabe, Kersten S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9293332/
https://www.ncbi.nlm.nih.gov/pubmed/34558792
http://dx.doi.org/10.1002/cbic.202100468

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9293332/
https://www.ncbi.nlm.nih.gov/pubmed/34558792
http://dx.doi.org/10.1002/cbic.202100468

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