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Modeling‐Assisted Design of Thermostable Benzaldehyde Lyases from Rhodococcus erythropolis for Continuous Production of α‐Hydroxy Ketones
Enantiopure α‐hydroxy ketones are important building blocks of active pharmaceutical ingredients (APIs), which can be produced by thiamine‐diphosphate‐dependent lyases, such as benzaldehyde lyase. Here we report the discovery of a novel thermostable benzaldehyde lyase from Rhodococcus erythropolis R...
Autores principales: | Peng, Martin, Siebert, Dominik L., Engqvist, Martin K. M., Niemeyer, Christof M., Rabe, Kersten S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9293332/ https://www.ncbi.nlm.nih.gov/pubmed/34558792 http://dx.doi.org/10.1002/cbic.202100468 |
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