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Farnesoid X receptor agonist for the treatment of chronic hepatitis B: A safety study

The nuclear farnesoid X receptor (FXR) regulates bile acid homeostasis and is a drug target for metabolic liver diseases. FXR also plays an important role in hepatitis B virus (HBV) DNA transcription. In vitro and in mice, FXR agonist treatment leads to inhibition of viral replication and a decline...

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Detalles Bibliográficos
Autores principales: Erken, Robin, Andre, Patrice, Roy, Elise, Kootstra, Neeltje, Barzic, Noelie, Girma, Hugo, Laveille, Christian, Radreau‐Pierini, Pauline, Darteil, Raphael, Vonderscher, Jacky, Scalfaro, Pietro, Tangkijvanich, Pisit, Flisiak, Robert, Reesink, Henk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9293351/
https://www.ncbi.nlm.nih.gov/pubmed/34467593
http://dx.doi.org/10.1111/jvh.13608