High Fidelity Enzyme‐Free Primer Extension with an Ethynylpyridone Thymidine Analog

High fidelity base pairing is important for the transmission of genetic information. Weak base pairs can lower fidelity, complicating sequencing, amplification and replication of DNA. Thymidine 5′‐monophosphate (TMP) is the most weakly pairing nucleotide among the canonical deoxynucleotides, causing...

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Detalles Bibliográficos
Autores principales: Han, Jianyang, Kervio, Eric, Richert, Clemens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9293356/
https://www.ncbi.nlm.nih.gov/pubmed/34559417
http://dx.doi.org/10.1002/chem.202102996

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9293356/
https://www.ncbi.nlm.nih.gov/pubmed/34559417
http://dx.doi.org/10.1002/chem.202102996

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