Inhibition of tumor‐associated macrophages by trabectedin improves the antitumor adaptive immunity in response to anti‐PD‐1 therapy

A considerable proportion of cancer patients are resistant or only partially responsive to immune checkpoint blockade immunotherapy. Tumor‐Associated Macrophages (TAMs) infiltrating the tumor stroma suppress the adaptive immune responses and, hence, promote tumor immune evasion. Depletion of TAMs or...

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Detalles Bibliográficos
Autores principales: Belgiovine, Cristina, Frapolli, Roberta, Liguori, Manuela, Digifico, Elisabeth, Colombo, Federico Simone, Meroni, Marina, Allavena, Paola, D'Incalci, Maurizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Tumor immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9293411/
https://www.ncbi.nlm.nih.gov/pubmed/34570376
http://dx.doi.org/10.1002/eji.202149379

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9293411/
https://www.ncbi.nlm.nih.gov/pubmed/34570376
http://dx.doi.org/10.1002/eji.202149379

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