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Kallikrein augments the anticoagulant function of the protein C system in thrombin generation

BACKGROUND: Genetics play a significant role in coagulation phenotype and venous thromboembolism risk. Resistance to the anticoagulant activated protein C (APC) is an established risk for thrombosis. Herein, we explored the genetic determinants of thrombin generation (TG) and thrombomodulin (TM)‐mod...

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Detalles Bibliográficos
Autores principales: Wan, Jun, Vadaq, Nadira, Konings, Joke, Jaeger, Martin, Kumar, Vinod, de Laat, Bas, Joosten, Leo, Netea, Mihai G., van der Ven, Andre J., de Groot, Philip G., de Mast, Quirijn, Roest, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9293419/
https://www.ncbi.nlm.nih.gov/pubmed/34532976
http://dx.doi.org/10.1111/jth.15530