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Kallikrein augments the anticoagulant function of the protein C system in thrombin generation
BACKGROUND: Genetics play a significant role in coagulation phenotype and venous thromboembolism risk. Resistance to the anticoagulant activated protein C (APC) is an established risk for thrombosis. Herein, we explored the genetic determinants of thrombin generation (TG) and thrombomodulin (TM)‐mod...
Autores principales: | Wan, Jun, Vadaq, Nadira, Konings, Joke, Jaeger, Martin, Kumar, Vinod, de Laat, Bas, Joosten, Leo, Netea, Mihai G., van der Ven, Andre J., de Groot, Philip G., de Mast, Quirijn, Roest, Mark |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9293419/ https://www.ncbi.nlm.nih.gov/pubmed/34532976 http://dx.doi.org/10.1111/jth.15530 |
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