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Silencing of TLR4 Inhibits Atrial Fibrosis and Susceptibility to Atrial Fibrillation via Downregulation of NLRP3-TGF-β in Spontaneously Hypertensive Rats

INTRODUCTION: This study was aimed at exploring whether silencing of TLR4 could inhibit atrial fibrosis and susceptibility to atrial fibrillation (AF) by regulating NLRP3-TGF-β in hypertensive rats. METHODS: Spontaneously hypertensive rats (SHRs) were transfected with either a virus containing TLR4-...

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Detalles Bibliográficos
Autores principales: Ge, Chenliang, Zhao, Yaxin, Liang, Yuming, He, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9293556/
https://www.ncbi.nlm.nih.gov/pubmed/35860690
http://dx.doi.org/10.1155/2022/2466150