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Structural variations between small alarmone hydrolase dimers support different modes of regulation of the stringent response

The bacterial stringent response involves wide-ranging metabolic reprogramming aimed at increasing long-term survivability during stress conditions. One of the hallmarks of the stringent response is the production of a set of modified nucleotides, known as alarmones, which affect a multitude of cell...

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Detalles Bibliográficos
Autores principales: Bisiak, Francesco, Chrenková, Adriana, Zhang, Sheng-Da, Pedersen, Jannik N., Otzen, Daniel E., Zhang, Yong E., Brodersen, Ditlev E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9293644/
https://www.ncbi.nlm.nih.gov/pubmed/35714769
http://dx.doi.org/10.1016/j.jbc.2022.102142