Structural biology of ex vivo mammalian prions

The structures of prion protein (PrP)–based mammalian prions have long been elusive. However, cryo-EM has begun to reveal the near-atomic resolution structures of fully infectious ex vivo mammalian prion fibrils as well as relatively innocuous synthetic PrP amyloids. Comparisons of these various typ...

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Detalles Bibliográficos
Autores principales: Artikis, Efrosini, Kraus, Allison, Caughey, Byron
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
JBC Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9293645/
https://www.ncbi.nlm.nih.gov/pubmed/35752366
http://dx.doi.org/10.1016/j.jbc.2022.102181

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9293645/
https://www.ncbi.nlm.nih.gov/pubmed/35752366
http://dx.doi.org/10.1016/j.jbc.2022.102181

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