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Structural basis for c-di-AMP–dependent regulation of the bacterial stringent response by receptor protein DarB

The bacterial second messenger c-di-AMP controls essential cellular processes, including potassium and osmolyte homeostasis. This makes synthesizing enzymes and components involved in c-di-AMP signal transduction intriguing as potential targets for drug development. The c-di-AMP receptor protein Dar...

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Detalles Bibliográficos
Autores principales: Heidemann, Jana L., Neumann, Piotr, Krüger, Larissa, Wicke, Dennis, Vinhoven, Liza, Linden, Andreas, Dickmanns, Achim, Stülke, Jörg, Urlaub, Henning, Ficner, Ralf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9293649/
https://www.ncbi.nlm.nih.gov/pubmed/35714772
http://dx.doi.org/10.1016/j.jbc.2022.102144