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Non-small molecule PROTACs (NSM-PROTACs): Protein degradation kaleidoscope

The proteolysis targeting chimeras (PROTACs) technology has been rapidly developed since its birth in 2001, attracting rapidly growing attention of scientific institutes and pharmaceutical companies. At present, a variety of small molecule PROTACs have entered the clinical trial. However, as small m...

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Detalles Bibliográficos
Autores principales: Ma, Sinan, Ji, Jianai, Tong, Yuanyuan, Zhu, Yuxuan, Dou, Junwei, Zhang, Xian, Xu, Shicheng, Zhu, Tianbao, Xu, Xiaoli, You, Qidong, Jiang, Zhengyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9293674/
https://www.ncbi.nlm.nih.gov/pubmed/35865099
http://dx.doi.org/10.1016/j.apsb.2022.02.022