Retinoic acid can improve autophagy through depression of the PI3K-Akt-mTOR signaling pathway via RARα to restore spermatogenesis in cryptorchid infertile rats

Cryptorchidism-caused adult infertility is a common component of idiopathic reasons for male infertility. Retinoic acid (RA) has a vital effect on the spermatogenesis process. Here, we found that the expression of c-Kit, Stra8, and Sycp3 could be up-regulated via the activation of retinoic acid rece...

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Detalles Bibliográficos
Autores principales: Long, Chunlan, Zhou, Yu, Shen, Lianju, Yu, Yihang, Hu, Dong, Liu, Xing, Lin, Tao, He, Dawei, Xu, Tao, Zhang, Deying, Zhu, Jing, Wei, Guanghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chongqing Medical University 2021
Materias:
Full Length Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9293722/
https://www.ncbi.nlm.nih.gov/pubmed/35873030
http://dx.doi.org/10.1016/j.gendis.2021.03.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9293722/
https://www.ncbi.nlm.nih.gov/pubmed/35873030
http://dx.doi.org/10.1016/j.gendis.2021.03.006

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