Why 90% of clinical drug development fails and how to improve it?

Ninety percent of clinical drug development fails despite implementation of many successful strategies, which raised the question whether certain aspects in target validation and drug optimization are overlooked? Current drug optimization overly emphasizes potency/specificity using structure‒activit...

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Detalles Bibliográficos
Autores principales: Sun, Duxin, Gao, Wei, Hu, Hongxiang, Zhou, Simon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Perspective
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9293739/
https://www.ncbi.nlm.nih.gov/pubmed/35865092
http://dx.doi.org/10.1016/j.apsb.2022.02.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9293739/
https://www.ncbi.nlm.nih.gov/pubmed/35865092
http://dx.doi.org/10.1016/j.apsb.2022.02.002

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