Cholenic acid derivative UniPR1331 impairs tumor angiogenesis via blockade of VEGF/VEGFR2 in addition to Eph/ephrin

Angiogenesis, the formation of new blood vessels from preexisting ones, is crucial for tumor growth and metastatization, and is considered a promising therapeutic target. Unfortunately, drugs directed against a specific proangiogenic growth factor or receptor turned out to be of limited benefit for...

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Detalles Bibliográficos
Autores principales: Rusnati, Marco, Paiardi, Giulia, Tobia, Chiara, Urbinati, Chiara, Lodola, Alessio, D’Ursi, Pasqualina, Corrado, Miriam, Castelli, Riccardo, Wade, Rebecca C., Tognolini, Massimiliano, Chiodelli, Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9293752/
https://www.ncbi.nlm.nih.gov/pubmed/34426652
http://dx.doi.org/10.1038/s41417-021-00379-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9293752/
https://www.ncbi.nlm.nih.gov/pubmed/34426652
http://dx.doi.org/10.1038/s41417-021-00379-5

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