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Combined proteomic and biochemical analyses redefine the consensus sequence requirement for epidermal growth factor-like domain hydroxylation

Epidermal growth factor-like domains (EGFDs) have important functions in cell–cell signaling. Both secreted and cell surface human EGFDs are subject to extensive modifications, including aspartate and asparagine residue C3-hydroxylations catalyzed by the 2-oxoglutarate oxygenase aspartate/asparagine...

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Detalles Bibliográficos
Autores principales: Brewitz, Lennart, Onisko, Bruce C., Schofield, Christopher J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9293771/
https://www.ncbi.nlm.nih.gov/pubmed/35700824
http://dx.doi.org/10.1016/j.jbc.2022.102129