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Combined proteomic and biochemical analyses redefine the consensus sequence requirement for epidermal growth factor-like domain hydroxylation

Epidermal growth factor-like domains (EGFDs) have important functions in cell–cell signaling. Both secreted and cell surface human EGFDs are subject to extensive modifications, including aspartate and asparagine residue C3-hydroxylations catalyzed by the 2-oxoglutarate oxygenase aspartate/asparagine...

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Detalles Bibliográficos
Autores principales:	Brewitz, Lennart, Onisko, Bruce C., Schofield, Christopher J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9293771/ https://www.ncbi.nlm.nih.gov/pubmed/35700824 http://dx.doi.org/10.1016/j.jbc.2022.102129

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